Publications - FIDMAG, Fundation for research

COOKIES USE
We use necessary system cookies for the correct functioning of the website and optional Google Analytics cookies to obtain visit statistics. +info

Cookies config

Necessary

The necessary cookies are absolutely essential for the website to work properly. This category only includes cookies that guarantee basic website security and functionality. These cookies do not store any personal information.

Name	Proveedor	Propiedad	Finalidad	Caducidad
_GRECAPTCHA	google.com	Own	provide antispam protection with the reCaptcha service	6 months
cc_cookie_accept	fidmag.org	Own	Usada per confirmar que l'usuari ha confirmat / refusat les cookies (i quins tipus accepta)	1 any
WEB_SESSION	fidmag.org	Own	Cookie técnica: cookie de sessió PHP. Guarda l'id de sessió d'usuari.	al acabar la sessió

Analisys

Analytical cookies are used to understand how visitors interact with the website. These cookies help to provide information on meters, the name of visitors, the percentage of bounces, the font of the traffic, etc.

Name	Proveedor	Propiedad	Finalidad	Caducidad
_ga	Google Analytics	From third parties	Cookie d'anàlisi o mesurament: Identifica els usuaris i proporciona informació sobre com els usuaris troben la pàgina web i com la utilitzen per a realització d'Informes estadístics	2 anys
_gat_gtag_UA_141706552_1	Google Analytics	From third parties	Cookie d'anàlisi o mesurament: Tracking per part de google per google analytics	1 minut
_gid	Google Analytics	From third parties	Cookie d'anàlisi o mesurament: S'usa per limitar el percentatge de sol·licituds	24 hores

Configure Reject all Accept

Home
> Research

Back to results

FI
3.923

25819935

2015 Schizophrenia Research

Premorbid adjustment and clinical correlates of cognitive impairment in first-episode psychosis. The PEPsCog Study.

Cuesta MJ, Sánchez-Torres AM, Cabrera B, Bioque M, Merchán-Naranjo J, Corripio I, González-Pinto A, Lobo A, Bombín I, de la Serna E, Sanjuan J, Parellada M, Saiz-Ruiz J, Bernardo M

Limited service to collaborators of the network of Sisters Hospitalarias Centers. You will receive a message in your email with a link to download this article.

Abstract

The extent to which socio-demographic, clinical, and premorbid adjustment variables contribute to cognitive deficits in first-episode schizophrenia spectrum disorders remains to be ascertained.226 first-episode psychosis patients and 225 healthy controls were assessed in the PEPsCog study, as part of the PEPs study.Patients showed slight to moderate cognitive impairment, verbal memory being the domain most impaired compared to controls. Broad affective spectrum patients had better premorbid IQ and outperformed the schizophrenia and other psychosis groups in executive function, and had better global cognitive function than the schizophrenia group. Adolescent premorbid adjustment together with age, gender, parental socio-economic status, and mean daily antipsychotic doses were the factors that best explained patients' cognitive performance. General and adolescent premorbid adjustment, age and parental socio-economic status were the best predictors of cognitive performance in controls.Poorer premorbid adjustment together with socio-demographic factors and higher daily antipsychotic doses were related to a generalized cognitive impairment and to a lower premorbid intellectual reserve, suggesting that neurodevelopmental impairment was present before illness onset.