COOKIES USE We use necessary system cookies for the correct functioning of the website and optional Google Analytics cookies to obtain visit statistics. +info
Cookies config
Necessary
The necessary cookies are absolutely essential for the website to work properly. This category only includes cookies that guarantee basic website security and functionality. These cookies do not store any personal information.
Name
Proveedor
Propiedad
Finalidad
Caducidad
+info
_GRECAPTCHA
google.com
Own
provide antispam protection with the reCaptcha service
6 months
cc_cookie_accept
fidmag.org
Own
Usada per confirmar que l'usuari ha confirmat / refusat les cookies (i quins tipus accepta)
1 any
WEB_SESSION
fidmag.org
Own
Cookie técnica: cookie de sessió PHP. Guarda l'id de sessió d'usuari.
al acabar la sessió
Analisys
Analytical cookies are used to understand how visitors interact with the website. These cookies help to provide information on meters, the name of visitors, the percentage of bounces, the font of the traffic, etc.
Name
Proveedor
Propiedad
Finalidad
Caducidad
+info
_ga
Google Analytics
From third parties
Cookie d'anàlisi o mesurament: Identifica els usuaris i proporciona informació sobre com els usuaris troben la pàgina web i com la utilitzen per a realització d'Informes estadístics
2 anys
_gat_gtag_UA_141706552_1
Google Analytics
From third parties
Cookie d'anàlisi o mesurament: Tracking per part de google per google analytics
1 minut
_gid
Google Analytics
From third parties
Cookie d'anàlisi o mesurament: S'usa per limitar el percentatge de sol·licituds
Neural correlates of disturbance in the sense of agency in schizophrenia: An fMRI study using the 'enfacement' paradigm.
Salgado-Pineda P, Fuentes-Claramonte P, Spanlang B, Pomes A, Landin-Romero R, Portillo F, Bosque C, Franquelo JC, Teixido C, Sarró S, Salvador R, Pomarol-Clotet E
Limited service to collaborators of the network of Sisters Hospitalarias Centers. You will receive a message in your email with a link to download this article.
Abstract
An altered sense of self-awareness and agency has been proposed to underlie symptoms of schizophrenia. In this study, we used the enfacement illusion paradigm - in which perception of another person's face leads to changes in perception of one's own peri-personal space - to examine the brain correlates of the sense of agency and its potential disruption in schizophrenia. Thirty-three schizophrenic patients and 27 healthy controls underwent fMRI scanning during performance of a task designed to elicit the enfacement illusion. Activations were examined using whole-brain analysis and also in an a priori identified region of interest (ROI) in the temporoparietal junction (TPJ), a region that has been described as involved in self/other differentiation and sense of agency. Both groups showed a pattern of cortical activation involving the pre and postcentral cortex, Rolandic operculum, insula, parietal, temporal and occipital cortex bilaterally as well as TPJ (but only right-side in patients). Examination of the TPJ ROI revealed significantly reduced activation on the left in the patients that was associated with poorer insight. The findings suggest brain functional abnormality in schizophrenia related to the formation or maintenance of processes related to self and/or agency. Decreased function in the TPJ may have a role in the impaired insight seen in patients with the disorder.